Improving culture performance and antibody production in CHO cell culture processes by reducing the Warburg effect. Improved Performance in Mammalian Cell Perfusion Cultures by Growth Inhibition. Zinc supplementation increases protein titer of recombinant CHO cells.ĭevelopment of a shake tube-based scale-down model for perfusion cultures. Process intensification in fed-batch production bioreactors using non-perfusion seed cultures. Modernizing Storage Conditions for Fresh Osteochondral Allografts by Optimizing Viability at Physiologic Temperatures and Conditions. Insight into the roles of tyrosine on rCHO cell performance in fed-batch cultures. Using Metabolomics to Identify Cell Line-Independent Indicators of Growth Inhibition for Chinese Hamster Ovary Cell-based Bioprocesses.Ĭomparing two automated high throughput viable-cell counting systems for cell culture applications.ĭevelopment and Qualification of a Scale-Down Mammalian Cell Culture Model and Application in Design Space Development by Definitive Screening Design. Raman spectroscopic based chemometric models to support a dynamic capacitance based cell culture feeding strategy. Stable overexpression of mutated PTEN in Chinese hamster ovary cells enhances their performance and therapeutic antibody production.Įffects of Caffeine on Intervertebral Disc Cell Viability in a Whole Organ Culture Model.Įstablishment and optimization of a high-throughput mimic perfusion model in ambr 15. Mapping the molecular basis for growth related phenotypes in industrial producer CHO cell lines using differential proteomic analysis. Transduction of HEK293 Cells with BacMam Baculovirus Is an Efficient System for the Production of HIV-1 Virus-like Particles.ĭetermination of Chinese hamster ovary (CHO) cell densities and antibody titers from small volumes of cell culture supernatants using multivariate analysis and partial least squares regression of UV-Vis spectra. Soft-sensors application for automated feeding control in high-throughput mammalian cell cultures. N-1 Perfusion Platform Development Using a Capacitance Probe for Biomanufacturing. Kinetic modeling: A tool for temperature shift and feeding optimization in cell culture process development.

Ivcd cell culture